Quantitation of Ten Flavor Compounds in Unburned Tobacco Products.
نویسندگان
چکیده
Most research on unburned tobacco has focused on the harmful chemicals associated with the tobacco itself. However, certain flavor additives in tobacco products can pose additional health risks. Flavors like camphor, coumarin, pulegone, eugenol, methyl salicylate, menthol and diphenyl ether have exhibited biological activity and/or toxicity in both lab animals and humans. This publication presents a new GC/MS method for the quantitation of ten flavor compounds (eucalyptol, camphor, menthol, pulegone, ethyl salicylate, methyl salicylate, cinnamaldehyde, eugenol, diphenyl ether and coumarin) in a variety of tobacco products, including smokeless products and cigar filler. Excellent linearity (>0.997), accuracy (93.9% - 106.6%) and precision (C.V., 0.5% - 3.0%) were achieved for all flavor analytes measured. A summary of the concentrations of these flavors in selected international smokeless tobacco (SLT) products including zarda, quiwam, gutkha, and khaini varieties from Southeast Asia and snuff, clove cigarette filler and flavored cigar filler from the United States is reported. High concentrations of eugenol (2110 μg/g), coumarin (439 μg/g), camphor (1060 μg/g) and diphenyl ether (4840 μg/g) were found in selected products. Accurate identification and quantitation of potentially hazardous flavor compounds is important because they can exist in relatively high levels in some tobacco products, including international SLT products. We outline a versatile method which can be used to quantitate flavor compounds in multiple types of tobacco products.
منابع مشابه
Simultaneous Determination of Coumarin and Its Derivatives in Tobacco Products by Liquid Chromatography-Tandem Mass Spectrometry.
In this paper an analytical method based on high performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS) for the determination of coumarin and its derivatives in tobacco products was developed. The MS/MS fragmentation pathways of the eight coumarins were elucidated. The new analytical method was defined based on two main axes, an extraction procedure with acetonitrile...
متن کاملThe Nature of Tumor-promoting Agents in Tobacco Products1
The results available so far suggest to us the following tentative conclusions. First, there are at least two agents extracted by aqueous barium hydroxide from commercial cigarette tobacco that are required simultaneously in order to exhibit tumor-promoting activity. One of the agents is soluble in 80% methanol and is probably soluble in 95% methanol. The other is insoluble in 80% methanol and ...
متن کاملThe Effect of Sour Orange, Swingle Citrumelo and Troyer Citrange Rootstocks on the Peel Components of Kumquat (Fortunella Margarita)
Studies have shown that oxygenated compounds are important in beverage and food products. It seems that Citrus rootstocks have a profound influence on these factors. The goal of the present study is to investigate on rootstocks and these factors. Peel oil components were extracted using cold-press method and eluted using n-hexane. All compounds analyzed using GC and GC-MS. Data were analyzed u...
متن کاملComparison of Leaf Components of Sweet Orange and Sour Orange (Citrus Sp.)
studies had shown that oxygenated compounds were important in food products. It seems that Citrus species had a profound influence on this factor. The goal of the present study was to investigate on flavor components of two Citrus species. In the early week of June 2012, about 500 g of leaves were collected from many parts of the same trees. Leaf components were extracted using water distillati...
متن کاملComparison of Leaf Components of Sweet Orange and Sour Orange (Citrus Sp.)
Studies had shown that oxygenated compounds were important in food products. It seems that Citrus species had a profound influence on this factor. The goal of the present study was to investigate on flavor components of two Citrus species. In the early week of June 2012, about 500 g of leaves were collected from many parts of the same trees. Leaf components were extracted using water distillati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Analytical methods : advancing methods and applications
دوره 6 13 شماره
صفحات -
تاریخ انتشار 2014